Reticulon 4 antibody (AA 1-200)

Catalog No. ABIN596754

This anti-Reticulon 4 antibody is a Sheep Polyclonal antibody detecting Reticulon 4 in WB and ELISA. Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for Reticulon 4 antibody (AA 1-200) (ABIN596754)

Target: Reticulon 4 (RTN4)

Reactivity: Human, Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This Reticulon 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Reticulon 4 Antibody

Binding Specificity: AA 1-200

Specificity: Recognizes human Nogo-B. Species cross-reactivity: mouse.

Purification: Immunoaffinity purified

Immunogen: CHO cell-derived, recombinant human Nogo-B (rhNogo-B, aa1-200, Accession #NP_722550).

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), WB (1 μg/mL)

Usage: Suitable for use in ELISA and Suitable for use in Western blot: 1 μg/mL. ELISA: 0.5-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS, 5 % trehalose

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

References for anti-Reticulon 4 antibody (ABIN596754)

Vontell, Supramaniam, Wyatt-Ashmead, Gressens, Rutherford, Hagberg, Thornton: "Cellular mechanisms of toll-like receptor-3 activation in the thalamus are associated with white matter injury in the developing brain." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 3, pp. 273-85, (2015) (PubMed).

Target Details for Reticulon 4

Target: Reticulon 4 (RTN4)

Alternative Name: RTN4 / Nogo

Background: Name/Gene ID: RTN4
Family: Reticulon

Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP

Gene ID: 57142

NCBI Accession: NP_722550

UniProt: Q9NQC3

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome