STEAP3 antibody

Catalog No. ABIN5967731

This Rabbit Polyclonal antibody specifically detects STEAP3 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STEAP3 antibody (ABIN5967731)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STEAP3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human STEAP3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Alternative Name: STEAP3

Background:

Synonyms: 1010001D01Rik,Dudlin 2,Dudlin2,Dudulin 2,Dudulin-2,Dudulin2,h  pH yde,hTSAP6,Metalloreductase STEAP3,MGC93147,  pH yde,Six transmembrane epithelial antigen of prostate 3,Six transmembrane prostate protein 3,Six-transmembrane epithelial antigen of prostate 3,STEA 3,STEA3,STEAP 3,STEAP family member 3,STEAP family member 3 metalloreductase,STEAP3,STMP 3,STMP3,TSAP 6,TSAP6,Tumor suppressor activated pathway protein 6,Tumor suppressor  pH yde,Tumor suppressor-activated pathway protein 6

Background: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 55kDa

Calculated_MW: 50kDa/54kDa/55kDa

Gene ID: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis