ITGA2 antibody

Catalog No. ABIN5968272

The Rabbit Polyclonal anti-ITGA2 antibody has been validated for WB and IHC. It is suitable to detect ITGA2 in samples from Human, Mouse and Rat.

Quick Overview for ITGA2 antibody (ABIN5968272)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ITGA2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ITGA2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:100 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2

Background:

Synonyms: BR,CD 49b,CD49 antigen like family member B,CD49 antigen-like family member B,CD49b,CD49b antigen,Collagen receptor,DX5,Glycoprotein Ia deficiency included,GP Ia,GP Ia deficiency,included,GPIa,HPA 5 included,HPA5 included,Human platelet alloantigen system 5,Integrin alpha 2,Integrin alpha II,Integrin alpha-2,Integrin,alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor),ITA2,ITGA2,Platelet alloantigen Br(a),included,Platelet antigen Br,Platelet glycoprotein GPIa,Platelet glycoprotein Ia,Platelet glycoprotein Ia/IIa,Platelet membrane glycoprotein Ia,Platelet receptor for collagen,deficiency of,included,Very late activation protein 2 receptor alpha 2 subunit,VLA 2 alpha chain,VLA 2,VLA 2 subunit alpha,VLA-2 subunit alpha,VLA2,VLA2 receptor alpha 2 subunit,VLAA2

Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 150kDa

Calculated_MW: 129kDa

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex