PLAU antibody

Catalog No. ABIN600305

The Goat Polyclonal anti-PLAU antibody is suitable to detect PLAU in samples from Human. It has been validated for WB, ELISA, IHC, IHC (p), IHC (fro) and RIA.

Quick Overview for PLAU antibody (ABIN600305)

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PLAU antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Radioimmunoassay (RIA)

Product Details anti-PLAU Antibody

Specificity: Recognizes human Urokinase. Does not cross-react with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, thrombin). Human whole plasma or plasma proteins do not interfere with its binding to urokinase. Binds to human HMW-scuPA (54kD), HMW-tsuPA (52kD) and LMW-scuPA (33kD) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Also inhibits the synthetic substrate S2444.

Purification: Immunoaffinity purified

Immunogen: Native human Urokinase.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:5000), IHC, IHC-Fr (1:50), IHC-P (1:50), RIA, WB (1:50)

Usage: Suitable for use in RIA, ELISA, Western Blot, Dot Blot and Immunohistochemistry. Immunohistochemistry (Frozen, paraffin): 1:50. ELISA: 1:5000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS, mannitol

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for PLAU

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Alternative Name: PLAU / Urokinase / UPA

Background: Name/Gene ID: PLAU
Subfamily: Serine S1
Family: Protease

Synonyms: PLAU, BDPLT5, U-PA, U-plasminogen activator, URK, Urokinase, Plasminogen activator, urinary, QPD, UPA

Gene ID: 5328

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration