CD43 antibody

Catalog No. ABIN610088

The Mouse Monoclonal anti-CD43 antibody has been validated for FACS, WB, IHC and Func. It is suitable to detect CD43 in samples from Human. There are 2+ publications available.

Quick Overview for CD43 antibody (ABIN610088)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: DFT-1

Product Details anti-CD43 Antibody

Specificity: Epitope A of the CD43 Molecule on pMN of about 135 kd.

Purification: Protein A purified

Immunogen: Human KG-1 tumor cells.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, IHC, WB

Usage: Function: Partially induces apoptosis in hemopoietic progenitor cells and also induces hemopoietic aggregation. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-CD43 antibody (ABIN610088)

Kim, Feldman: "Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt." in: The Journal of biological chemistry, Vol. 277, Issue 30, pp. 27393-400, (2002) (PubMed).

Clancy, Rediske, Tang, Nijher, Frenkel, Philips, Abramson: "Outside-in signaling in the chondrocyte. Nitric oxide disrupts fibronectin-induced assembly of a subplasmalemmal actin/rho A/focal adhesion kinase signaling complex." in: The Journal of clinical investigation, Vol. 100, Issue 7, pp. 1789-96, (1997) (PubMed).

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background: Name/Gene ID: SPN

Synonyms: SPN, GPL115, Leukosialin, Leukocyte sialoglycoprotein, Galactoglycoprotein, GALGP, Sialophorin, LSN, CD43, CD43 antigen

Gene ID: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity