IL2 Receptor beta antibody

Catalog No. ABIN610366

This Mouse Monoclonal antibody specifically detects IL2 Receptor beta in FACS and Func. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for IL2 Receptor beta antibody (ABIN610366)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 9A2

Product Details anti-IL2 Receptor beta Antibody

Specificity: 75 kd b subunit CD122 of the high affinity interleukin-2 receptor.

Purification: Protein A purified

Immunogen: YT-1 acute human leukemia cells.

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Inhibits binding of IL-2 to IL-2R beta (CD122). The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-IL2 Receptor beta antibody (ABIN610366)

Hasegawa, Zinsser, Rhee, Vik-Mo, Davanger, Hay: "Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 698-720, (2003) (PubMed).

Martinez-Arca, Alberts, Zahraoui, Louvard, Galli: "Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth." in: The Journal of cell biology, Vol. 149, Issue 4, pp. 889-900, (2000) (PubMed).

Chapman, An, Barton, Jahn: "SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils." in: The Journal of biological chemistry, Vol. 269, Issue 44, pp. 27427-32, (1994) (PubMed).

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2RB / CD122

Background: Name/Gene ID: IL2RB
Family: Interleukin

Synonyms: IL2RB, CD122, CD122 antigen, IL-2 receptor subunit beta, IL15RB, Interleukin 15 receptor, beta, p70-75, IL-2R subunit beta, IL-2RB, Interleukin 2 receptor, beta

Gene ID: 3560

UniProt: P14784

Pathways: JAK-STAT Signaling, Growth Factor Binding