CD40 Ligand antibody

Catalog No. ABIN610381

This Mouse Monoclonal antibody specifically detects CD40 Ligand in WB, FACS, IHC, ELISA and Func. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CD40 Ligand antibody (ABIN610381)

Target: CD40 Ligand (CD40LG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Functional Studies (Func)

Clone: 24-31

Product Details anti-CD40 Ligand Antibody

Specificity: Immunoprecipitates a CD154 (gp39) molecule of about 39 kd.

Purification: Protein A purified

Immunogen: Human sgp39 fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo, Func, IHC, WB

Usage: Function: Blocks MLR, sgp39 induced human B cell proliferation and T cell dependent B cell differentiation. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-CD40 Ligand antibody (ABIN610381)

Ros-Baro, Lopez-Iglesias, Peiro, Bellido, Palacin, Zorzano, Camps: "Lipid rafts are required for GLUT4 internalization in adipose cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 21, pp. 12050-5, (2001) (PubMed).

Laporte, Oakley, Zhang, Holt, Ferguson, Caron, Barak: "The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 7, pp. 3712-7, (1999) (PubMed).

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD40LG / CD40L / CD154

Background: Name/Gene ID: CD40LG
Family: TNF

Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein

Gene ID: 959

UniProt: P29965

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints