BTLA antibody (Biotin)

Catalog No. ABIN610421

The Mouse Monoclonal anti-BTLA antibody has been validated for FACS and ELISA. It is suitable to detect BTLA in samples from Human. There are 2+ publications available.

Quick Overview for BTLA antibody (Biotin) (ABIN610421)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BTLA antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA

Clone: ANC5A5

Product Details anti-BTLA Antibody (Biotin)

Specificity: CD272 on the cell surface of human PBMC in Flow cytometry, and to recombinant CD272-muIg in EIA.

Purification: Protein A purified

Immunogen: Recombinant extracellular human CD272.

Type of Immunogen: Recombinant protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, Flo

Usage: ELISA: Detection. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-BTLA antibody (Biotin) (ABIN610421)

Lavitrano, Bacci, Forni, Lazzereschi, Di Stefano, Fioretti, Giancotti, Marfé, Pucci, Renzi, Wang, Stoppacciaro, Stassi, Sargiacomo, Sinibaldi, Turchi, Giovannoni, Della Casa, Seren, Rossi: "Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14230-5, (2002) (PubMed).

Woodman, Park, Cohen, Cheung, Chandra, Shirani, Tang, Jelicks, Kitsis, Christ, Factor, Tanowitz, Lisanti: "Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38988-97, (2002) (PubMed).

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: BTLA / CD272

Background: Name/Gene ID: BTLA

Synonyms: BTLA, BTLA1, B and T lymphocyte associated, CD272, B and T lymphocyte attenuator, B- and T-lymphocyte attenuator, CD272 antigen

Gene ID: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints