AIPL1 antibody (AA 1-384)

Catalog No. ABIN6136691

Product Details anti-AIPL1 Antibody

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Binding Specificity: AA 1-384

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIPL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSRQVGQPMH IIIGNMFKLE VWEILLTSMR VHEVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT CGLANMFAYH TLGYEDLDEL QKEPQPLVFV IELLQVDAPS DYQRETWNLS NHEKMKAVPV LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLILNYCQCL LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLQKV LELEPSMQKA VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATQPPAEPPT EPPAQSSTEP PAEPPTAPSA ELSAGPPAEP ATEPPPSPGH SLQH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human AIPL1 (NP_055151.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AIPL1

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Alternative Name: AIPL1 (AIPL1 Products)

Synonyms: AIPL1 antibody, lca4 antibody, aipl2 antibody, AIPL2 antibody, LCA4 antibody, A930007I01Rik antibody, aryl hydrocarbon receptor interacting protein like 1 antibody, aryl hydrocarbon receptor-interacting protein-like 1 antibody, AIPL1 antibody, aipl1 antibody, Aipl1 antibody

Background: Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5 % of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20 % of recessive LCA. Alternative splicing results in multiple transcript variants.,AIPL1,AIPL2,LCA4,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,AIPL1

Molecular Weight: 36 kDa/40 kDa/41 kDa/43 kDa

Gene ID: 23746

UniProt: Q9NZN9