ANO1 antibody (AA 628-731)
Quick Overview for ANO1 antibody (AA 628-731) (ABIN6136901)
Target
See all ANO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 628-731
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Sequence
- FKGRFVGRPG DYVYIFRSFR MEECAPGGCL MELCIQLSII MLGKQLIQNN LFEIGIPKMK KLIRYLKLKQ QSPPDHEECV KRKQRYEVDY NLEPFAGLTP EYME
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 628-731 of human ANO1 (NP_060513.5).
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Isotype
- IgG
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Application Notes
- WB,1:1000 - 1:2000,IF,1:100 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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Alternative Name
- ANO1
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Background
- Calcium-activated chloride channel (CaCC which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.,ANO1,DOG1,ORAOV2,TAOS2,TMEM16A,ANO1
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Molecular Weight
- 74 kDa/97 kDa/114 kDa
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Gene ID
- 55107
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UniProt
- Q5XXA6
Target
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