APITD1 antibody (AA 1-138)

Catalog No. ABIN6136987

The Rabbit Polyclonal anti-APITD1 antibody has been validated for WB. It is suitable to detect APITD1 in samples from Human.

Quick Overview for APITD1 antibody (AA 1-138) (ABIN6136987)

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APITD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APITD1 Antibody

Binding Specificity: AA 1-138

Sequence: MEEEAETEEQ QRFSYQQRLK AAVHYTVGCL CEEVALDKEM QFSKQTIAAI SELTFRQCEN FAKDLEMFAR HAKRTTINTE DVKLLARRSN SLLKYITDKS EEIAQINLER KAQKKKKSED GSKNSRQPAE AGVVESEN

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human APITD1 (NP_954988.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for APITD1

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Alternative Name: APITD1

Background: This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.,CENPS,APITD1,CENP-S,FAAP16,MHF1,Cell Biology & Developmental Biology,Cell Cycle,Centromere,APITD1

Molecular Weight: 9 kDa/15 kDa/19 kDa

Gene ID: 378708

UniProt: Q8N2Z9