Aprataxin antibody (AA 93-342)
Quick Overview for Aprataxin antibody (AA 93-342) (ABIN6137038)
Target
See all Aprataxin (APTX) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 93-342
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Sequence
- LYPYIVEFEE EAKNPGLETH RKRKRSGNSD SIERDAAQEA EAGTGLEPGS NSGQCSVPLK KGKDAPIKKE SLGHWSQGLK ISMQDPKMQV YKDEQVVVIK DKYPKARYHW LVLPWTSISS LKAVAREHLE LLKHMHTVGE KVIVDFAGSS KLRFRLGYHA IPSMSHVHLH VISQDFDSPC LKNKKHWNSF NTEYFLESQA VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ
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Cross-Reactivity
- Human
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 93-342 of human APTX (NP_001182178.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:20 - 1:50
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Aprataxin (APTX)
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Alternative Name
- APTX
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Background
- This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.,APTX,AOA,AOA1,AXA1,EAOH,EOAHA,FHA-HIT,aprataxin,Epigenetics & Nuclear Signaling,DNA Damage & Repair,APTX
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Molecular Weight
- 5 kDa/13 kDa/19-40 kDa
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Gene ID
- 54840
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UniProt
- Q7Z2E3
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Pathways
- DNA Damage Repair, Chromatin Binding
Target
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