Asialoglycoprotein Receptor 2 antibody (AA 58-287)

Catalog No. ABIN6137183

The Rabbit Polyclonal anti-Asialoglycoprotein Receptor 2 antibody has been validated for WB. It is suitable to detect Asialoglycoprotein Receptor 2 in samples from Human.

Quick Overview for Asialoglycoprotein Receptor 2 antibody (AA 58-287) (ABIN6137183)

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Binding Specificity: AA 58-287

Sequence: TGSQSAQLQA ELRSLKEAFS NFSSSTLTEV QAISTHGGSV GDKITSLGAK LEKQQQDLKA DHDALLFHLK HFPVDLRFVA CQMELLHSNG SQRTCCPVNW VEHQGSCYWF SHSGKAWAEA EKYCQLENAH LVVINSWEEQ KFIVQHTNPF NTWIGLTDSD GSWKWVDGTD YRHNYKNWAV TQPDNWHGHE LGGSEDCVEV QPDGRWNDDF CLQVYRWVCE KRRNATGEVA

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 58-287 of human ASGR2 (NP_550435.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ASGR2,ASGP-R2,ASGPR2,CLEC4H2,HBXBP,HL-2,Signal Transduction,ASGR2

Molecular Weight: 32 kDa/35 kDa

Gene ID: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis