Asialoglycoprotein Receptor 2 antibody (AA 80-311)

Catalog No. ABIN7193549

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Binding Specificity: AA 80-311

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. coli.

Clone: 2C6D11

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2 (ASGR2 Products)

Synonyms: ASGR2 antibody, asgr2 antibody, MGC137129 antibody, ASGP-R2 antibody, ASGPR2 antibody, CLEC4H2 antibody, HBXBP antibody, HL-2 antibody, Asgr antibody, Asgr-2 antibody, asialoglycoprotein receptor 2 antibody, C-type lectin domain family 10 member A antibody, ASGR2 antibody, clec10a antibody, Asgr2 antibody, LOC100347178 antibody

Background:

Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

Molecular Weight: 35 kDa

Gene ID: 433

Pathways: Thyroid Hormone Synthesis