ACCN1 antibody (AA 120-400)

Catalog No. ABIN6137189

This Rabbit Polyclonal antibody specifically detects ACCN1 in WB. It exhibits reactivity toward Human.

Quick Overview for ACCN1 antibody (AA 120-400) (ABIN6137189)

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACCN1 Antibody

Binding Specificity: AA 120-400

Sequence: NLQIPDPHLA DPSVLEALRQ KANFKHYKPK QFSMLEFLHR VGHDLKDMML YCKFKGQECG HQDFTTVFTK YGKCYMFNSG EDGKPLLTTV KGGTGNGLEI MLDIQQDEYL PIWGETEETT FEAGVKVQIH SQSEPPFIQE LGFGVAPGFQ TFVATQEQRL TYLPPPWGEC RSSEMGLDFF PVYSITACRI DCETRYIVEN CNCRMVHMPG DAPFCTPEQH KECAEPALGL LAEKDSNYCL CRTPCNLTRY NKELSMVKIP SKTSAKYLEK KFNKSEKYIS E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACCN1

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Alternative Name: ASIC2

Background: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.,ASIC2,ACCN,ACCN1,ASIC2a,BNC1,BNaC1,MDEG,hBNaC1,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,ASIC2

Molecular Weight: 57 kDa/62 kDa

Gene ID: 40

UniProt: Q16515

Pathways: Sensory Perception of Sound