ACCN1 antibody (AA 120-148)
Quick Overview for ACCN1 antibody (AA 120-148) (ABIN7479781)
Target
See all ACCN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-148
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Purpose
- ACCN1 Antibody / ASIC2
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse,Rat
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 120-148 from the human protein was used as the immunogen for this ACCN1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the ACCN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the ACCN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
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Alternative Name
- ACCN1
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Background
- Amiloride-sensitive cation channel neuronal 1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN1 may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
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UniProt
- Q16515
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Pathways
- Sensory Perception of Sound
Target
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