ATG5 antibody (AA 28-275)

Catalog No. ABIN6137264

This anti-ATG5 antibody is a Rabbit Polyclonal antibody detecting ATG5 in WB and IHC. Suitable for Human.

Quick Overview for ATG5 antibody (AA 28-275) (ABIN6137264)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ATG5 Antibody

Binding Specificity: AA 28-275

Sequence: TEREAEPYYL LLPRVSYLTL VTDKVKKHFQ KVMRQEDISE IWFEYEGTPL KWHYPIGLLF DLLASSSALP WNITVHFKSF PEKDLLHCPS KDAIEAHFMS CMKEADALKH KSQVINEMQK KDHKQLWMGL QNDRFDQFWA INRKLMEYPA EENGFRYIPF RIYQTTTERP FIQKLFRPVA ADGQLHTLGD LLKEVCPSAI DPEDGEKKNQ VMIHGIEPML ETPLQWLSEH LSYPDNFLHI SIIPQPTD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-275 of human ATG5 (NP_004840.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name: ATG5

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.,ATG5,APG5,APG5-LIKE,APG5L,ASP,hAPG5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,Cardiovascular,Heart,ATGs,ATG5

Molecular Weight: 22 kDa/32 kDa

Gene ID: 9474

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy