BCL3 antibody (AA 300-400)

Catalog No. ABIN6137509

This Rabbit Polyclonal antibody specifically detects BCL3 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for BCL3 antibody (AA 300-400) (ABIN6137509)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BCL3 Antibody

Binding Specificity: AA 300-400

Sequence: ANVNAQMYSG SSALHSASGR GLLPLVRTLV RSGADSSLKN CHNDTPLMVA RSRRVIDILR GKATRPASTS QPDPSPDRSA NTSPESSSRL SSNGLLSASP S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human BCL3 (NP_005169.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Alternative Name: BCL3

Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.,BCL3,BCL4,D19S37,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,NF-kB Signaling Pathway,BCL3

Molecular Weight: 47 kDa

Gene ID: 602

UniProt: P20749

Pathways: NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus