C4BPB antibody (AA 18-251)

Catalog No. ABIN6137775

The Rabbit Polyclonal anti-C4BPB antibody has been validated for WB. It is suitable to detect C4BPB in samples from Human.

Quick Overview for C4BPB antibody (AA 18-251) (ABIN6137775)

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BPB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C4BPB Antibody

Binding Specificity: AA 18-251

Sequence: SDEHCPELPP VDNSIFVAKE VEGQILGTYV CIKGYHLVGK KTLFCNASKE WDNTTTECRL GHCPDPVLVN GEFSSSGPVN VSDKITFMCN DHYILKGSNR SQCLEDHTWA PPFPICKSRD CDPPGNPVHG YFEGNNFTLG STISYYCEDR YYLVGVQEQQ CVDGEWSSAL PVCKLIQEAP KPECEKALLA FQESKNLCEA MENFMQQLKE SGMTMEELKY SLELKKAELK AKLL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Alternative Name: C4BPB

Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.,C4BPB,C4BP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C4BPB

Molecular Weight: 28 kDa

Gene ID: 725

UniProt: P20851

Pathways: Complement System