CA9 antibody (AA 52-151)

Catalog No. ABIN6137798

The Rabbit Polyclonal anti-CA9 antibody is suitable to detect CA9 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for CA9 antibody (AA 52-151) (ABIN6137798)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CA9 Antibody

Binding Specificity: AA 52-151

Sequence: GSSGEDDPLG EEDLPSEEDS PREEDPPGEE DLPGEEDLPG EEDLPEVKPK SEEEGSLKLE DLPTVEAPGD PQEPQNNAHR DKEGDDQSHW RYGGDPPWPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-151 of human Carbonic Anhydrase 9 (CA9/G250) (NP_001207.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: CA9

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.,CA9,CAIX,MN,Cancer,Signal Transduction,Endocrine & Metabolism,Cardiovascular,Hypoxia,CA9

Molecular Weight: 49 kDa

Gene ID: 768

UniProt: Q16790