CABLES1 antibody (AA 1-368)

Catalog No. ABIN6137804

The Rabbit Polyclonal anti-CABLES1 antibody has been validated for WB and IHC. It is suitable to detect CABLES1 in samples from Human.

Quick Overview for CABLES1 antibody (AA 1-368) (ABIN6137804)

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABLES1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CABLES1 Antibody

Binding Specificity: AA 1-368

Sequence: MLSKRGCHAR IYADFPIRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKNFKKIHFI KNMRQHDTRN GRIVLISGRR SFCSIFSVLP YRDSTQVGDL KLDGGRQSTG AVSLKEIIGL EGVELGADGK TVSYTQFLLP TNAFGARRNT IDSTSSFSQF RNLSHRSLSI GRASGTQGSL DTGSDLGDFM DYDPNLLDDP QWPCGKHKRV LIFPSYMTTV IDYVKPSDLK KDMNETFKEK FPHIKLTLSK IRSLKREMRK LAQEDCGLEE PTVAMAFVYF EKLALKGKLN KQNRKLCAGA CVLLAAKIGS DLKKHEVKHL IDKLEEKFRL NRRELIAFEF PVLVALEFAL HLPEHEVMPH YRRLVQSS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Alternative Name: CABLES1

Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.,CABLES1,CABL1,CABLES,HsT2563,IK3-1,Kinase,Cell Biology & Developmental Biology,Cell Cycle,CABLES1

Molecular Weight: 15 kDa/34 kDa/41 kDa/67 kDa

Gene ID: 91768

UniProt: Q8TDN4