Calpain 2 antibody (AA 350-680)

Catalog No. ABIN6137916

The Rabbit Polyclonal anti-Calpain 2 antibody has been validated for WB and IHC. It is suitable to detect Calpain 2 in samples from Human. There is 1 publication available.

Quick Overview for Calpain 2 antibody (AA 350-680) (ABIN6137916)

Target: Calpain 2 (CAPN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Calpain 2 Antibody

Binding Specificity: AA 350-680

Sequence: SDTYKKWKLT KMDGNWRRGS TAGGCRNYPN TFWMNPQYLI KLEEEDEDEE DGESGCTFLV GLIQKHRRRQ RKMGEDMHTI GFGIYEVPEE LSGQTNIHLS KNFFLTNRAR ERSDTFINLR EVLNRFKLPP GEYILVPSTF EPNKDGDFCI RVFSEKKADY QAVDDEIEAN LEEFDISEDD IDDGFRRLFA QLAGEDAEIS AFELQTILRR VLAKRQDIKS DGFSIETCKI MVDMLDSDGS GKLGLKEFYI LWTKIQKYQK IYREIDVDRS GTMNSYEMRK ALEEAGFKMP CQLHQVIVAR FADDQLIIDF DNFVRCLVRL ETLFKIFKQL D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-680 of human Calpain 2 (NP_001739.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Calpain 2 antibody (ABIN6137916)

Wan, Wang, Xiong, Xiang, Li, Wang, Liu, Niu, Peng, Jiang, Chai: "Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing." in: Scientific reports, Vol. 6, pp. 36589, (2018) (PubMed).

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: CAPN2

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.,CAPN2,CANP2,CANPL2,CANPml,mCANP,calpain 2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Endocrine & Metabolism,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CAPN2

Molecular Weight: 71 kDa/79 kDa

Gene ID: 824

UniProt: P17655