Caveolin 3 antibody (AA 1-100)

Catalog No. ABIN6137994

The Rabbit Polyclonal anti-Caveolin 3 antibody has been validated for WB. It is suitable to detect Caveolin 3 in samples from Human.

Quick Overview for Caveolin 3 antibody (AA 1-100) (ABIN6137994)

Target: Caveolin 3 (CAV3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caveolin 3 Antibody

Binding Specificity: AA 1-100

Sequence: MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Caveolin-3 (NP_001225.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caveolin 3

Target: Caveolin 3 (CAV3)

Alternative Name: CAV3

Background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.,CAV3,LGMD1C,LQT9,VIP-21,VIP21,Signal Transduction,ErbB-HER Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,CAV3

Molecular Weight: 17 kDa

Gene ID: 859

UniProt: P56539

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity