CCT4 antibody (AA 130-390)

Catalog No. ABIN6138108

Product Details anti-CCT4 Antibody

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Binding Specificity: AA 130-390

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: PTIISESFQK ALEKGIEILT DMSRPVELSD RETLLNSATT SLNSKVVSQY SSLLSPMSVN AVMKVIDPAT ATSVDLRDIK IVKKLGGTID DCELVEGLVL TQKVSNSGIT RVEKAKIGLI QFCLSAPKTD MDNQIVVSDY AQMDRVLREE RAYILNLVKQ IKKTGCNVLL IQKSILRDAL SDLALHFLNK MKIMVIKDIE REDIEFICKT IGTKPVAHID QFTADMLGSA ELAEEVNLNG SGKLLKITGC ASPGKTVTIV V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-390 of human CCT4 (NP_006421.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCT4

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Alternative Name: CCT4 (CCT4 Products)

Synonyms: zgc:65789 antibody, zgc:77192 antibody, Cct4 antibody, Dmel\\CG5525 antibody, Tcp-1delta antibody, Tcp1-delta antibody, cct4 antibody, MGC89275 antibody, CCT4 antibody, DKFZp459D1424 antibody, LOC100225853 antibody, cctd antibody, CCT-DELTA antibody, Cctd antibody, SRB antibody, 2610204B21Rik antibody, A45 antibody, C78323 antibody, chaperonin containing TCP1, subunit 4 (delta) antibody, chaperonin containing TCP1 subunit 4 antibody, chaperonin containing TCP1 subunit 4 L homeolog antibody, CG5525 gene product from transcript CG5525-RA antibody, chaperonin containing Tcp1, subunit 4 (delta) antibody, T-complex protein 1 subunit delta antibody, cct4 antibody, CCT4 antibody, cct4.L antibody, CG5525 antibody, Cct4 antibody, cct-4 antibody

Background: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008],CCT4,CCT-DELTA,Cctd,SRB,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,CCT4

Molecular Weight: 54 kDa/57 kDa

Gene ID: 10575

UniProt: P50991

Pathways: Embryonic Body Morphogenesis