CETN2 antibody (AA 1-172)

Catalog No. ABIN6138442

The Rabbit Polyclonal anti-CETN2 antibody has been validated for WB and IF. It is suitable to detect CETN2 in samples from Human. There is 1 publication available.

Quick Overview for CETN2 antibody (AA 1-172) (ABIN6138442)

Target: CETN2 (Centrin, EF-Hand Protein, 2 (CETN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CETN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CETN2 Antibody

Binding Specificity: AA 1-172

Sequence: MASNFKKANM ASSSQRKRMS PKPELTEEQK QEIREAFDLF DADGTGTIDV KELKVAMRAL GFEPKKEEIK KMISEIDKEG TGKMNFGDFL TVMTQKMSEK DTKEEILKAF KLFDDDETGK ISFKNLKRVA KELGENLTDE ELQEMIDEAD RDGDGEVSEQ EFLRIMKKTS LY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CETN2 (NP_004335.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CETN2 antibody (ABIN6138442)

Anurag, Punturi, Hoog, Bainbridge, Ellis, Haricharan: "Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 19, pp. 4887-4899, (2018) (PubMed).

Target Details for CETN2

Target: CETN2 (Centrin, EF-Hand Protein, 2 (CETN2))

Alternative Name: CETN2

Background: Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.,CETN2,CALT,CEN2,centrin-2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,Calcium Signaling,CETN2

Molecular Weight: 19 kDa

Gene ID: 1069

UniProt: P41208

Pathways: DNA Damage Repair, M Phase