CHD4 antibody (AA 1520-1690)

Catalog No. ABIN6138512

This Rabbit Polyclonal antibody specifically detects CHD4 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CHD4 antibody (AA 1520-1690) (ABIN6138512)

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CHD4 Antibody

Binding Specificity: AA 1520-1690

Sequence: ELAEVEENKK MSQPGSPSPK TPTPSTPGDT QPNTPAPVPP AEDGIKIEEN SLKEEESIEG EKEVKSTAPE TAIECTQAPA PASEDEKVVV EPPEGEEKVE KAEVKERTEE PMETEPKGAA DVEKVEEKSA IDLTPIVVED KEEKKEEEEK KEVMLQNGET PKDLNDEKQK K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHD4

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Alternative Name: CHD4

Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Immunology & Inflammation,CHD4

Molecular Weight: 218 kDa/220 kDa

Gene ID: 1108

UniProt: Q14839