Chloride Channel 5 antibody (AA 637-816)

Catalog No. ABIN6138667

The Rabbit Polyclonal anti-Chloride Channel 5 antibody has been validated for WB. It is suitable to detect Chloride Channel 5 in samples from Human.

Quick Overview for Chloride Channel 5 antibody (AA 637-816) (ABIN6138667)

Target: Chloride Channel 5 (CLCN5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chloride Channel 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Chloride Channel 5 Antibody

Binding Specificity: AA 637-816

Sequence: YPFLEAKEEF AHKTLAMDVM KPRRNDPLLT VLTQDSMTVE DVETIISETT YSGFPVVVSR ESQRLVGFVL RRDLIISIEN ARKKQDGVVS TSIIYFTEHS PPLPPYTPPT LKLRNILDLS PFTVTDLTPM EIVVDIFRKL GLRQCLVTHN GRLLGIITKK DVLKHIAQMA NQDPDSILFN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_001121370.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Chloride Channel 5

Target: Chloride Channel 5 (CLCN5)

Alternative Name: CLCN5

Background: This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.,CLCN5,CLC5,CLCK2,ClC-5,DENTS,NPHL1,NPHL2,XLRH,XRN,hCIC-K2,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,CLCN5

Molecular Weight: 83 kDa/90 kDa

Gene ID: 1184

UniProt: P51795