Chloride Channel 5 antibody

Catalog No. ABIN7227938

The Rabbit Polyclonal anti-Chloride Channel 5 antibody is suitable to detect Chloride Channel 5 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Chloride Channel 5 antibody (ABIN7227938)

Target: Chloride Channel 5 (CLCN5)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chloride Channel 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Chloride Channel 5 Antibody

Purpose: Rabbit Anti-CLCN5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLCN5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLCN5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Chloride Channel 5

Target: Chloride Channel 5 (CLCN5)

Alternative Name: CLCN5

Background: H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. The Chloride Voltage-Gated Channel 5 is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 82kD

Gene ID: 1184

UniProt: P51795