COPS6 antibody (AA 58-327)

Catalog No. ABIN6138885

This Rabbit Polyclonal antibody specifically detects COPS6 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for COPS6 antibody (AA 58-327) (ABIN6138885)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COPS6 Antibody

Binding Specificity: AA 58-327

Sequence: MRSQEGRPVQ VIGALIGKQE GRNIEVMNSF ELLSHTVEEK IIIDKEYYYT KEEQFKQVFK ELEFLGWYTT GGPPDPSDIH VHKQVCEIIE SPLFLKLNPM TKHTDLPVSV FESVIDIING EATMLFAELT YTLATEEAER IGVDHVARMT ATGSGENSTV AEHLIAQHSA IKMLHSRVKL ILEYVKASEA GEVPFNHEIL REAYALCHCL PVLSTDKFKT DFYDQCNDVG LMAYLGTITK TCNTMNQFVN KFNVLYDRQG IGRRMRGLFF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6 (NP_006824.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Alternative Name: COPS6

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.,COPS6,CSN6,MOV34-34KD,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,COPS6

Molecular Weight: 36 kDa

Gene ID: 10980

UniProt: Q7L5N1

Pathways: Cell Division Cycle