COQ3 antibody (AA 50-369)

Catalog No. ABIN6138894

The Rabbit Polyclonal anti-COQ3 antibody (ABIN6138894) specifically detects COQ3 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for COQ3 antibody (AA 50-369) (ABIN6138894)

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COQ3 Antibody

Binding Specificity: AA 50-369

Sequence: PGVFNEYRTI WFKSYRTIFS CLNRIKSFRY PWARLYSTSQ TTVDSGEVKT FLALAHKWWD EQGVYAPLHS MNDLRVPFIR DNLLKTIPNH QPGKPLLGMK ILDVGCGGGL LTEPLGRLGA SVIGIDPVDE NIKTAQCHKS FDPVLDKRIE YRVCSLEEIV EETAETFDAV VASEVVEHVI DLETFLQCCC QVLKPGGSLF ITTINKTQLS YALGIVFSEQ IASIVPKGTH TWEKFVSPET LESILESNGL SVQTVVGMLY NPFSGYWHWS ENTSLNYAAY AVKSRVQEHP ASAEFVLKGE TEELQANACT NPAVHEKLKK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-369 of human COQ3 (NP_059117.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COQ3

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Alternative Name: COQ3

Background: Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008],COQ3,DHHBMT,DHHBMTASE,UG0215E05,bA9819.1,coenzyme Q3,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COQ3

Molecular Weight: 41 kDa

Gene ID: 51805

UniProt: Q9NZJ6

Pathways: Methionine Biosynthetic Process