CPSF2 antibody (AA 450-700)

Catalog No. ABIN6138966

Cited in 1 publication. The Rabbit Polyclonal anti-CPSF2 antibody (ABIN6138966) specifically detects CPSF2 in WB. The antibody is reactive with Human samples.

Quick Overview for CPSF2 antibody (AA 450-700) (ABIN6138966)

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CPSF2 Antibody

Binding Specificity: AA 450-700

Sequence: KGSFFKQAKK SYPMFPAPEE RIKWDEYGEI IKPEDFLVPE LQATEEEKSK LESGLTNGDE PMDQDLSDVP TKCISTTESI EIKARVTYID YEGRSDGDSI KKIINQMKPR QLIIVHGPPE ASQDLAECCR AFGGKDIKVY MPKLHETVDA TSETHIYQVR LKDSLVSSLQ FCKAKDAELA WIDGVLDMRV SKVDTGVILE EGELKDDGED SEMQVEAPSD SSVIAQQKAM KSLFGDDEKE TGEESEIIPT L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CPSF2 antibody (ABIN6138966)

Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

Target Details for CPSF2

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Alternative Name: CPSF2

Background: Component of the cleavage and polyadenylation specificity factor (CPSF complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A polymerase and other factors to bring about cleavage and poly(A addition. Involved in the histone 3' end pre-mRNA processing.,CPSF2,CPSF100,Epigenetics & Nuclear Signaling,CPSF2

Molecular Weight: 88 kDa

Gene ID: 53981

UniProt: Q9P2I0