CRHBP antibody (AA 25-322)

Catalog No. ABIN6139030

The Rabbit Polyclonal anti-CRHBP antibody is suitable to detect CRHBP in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for CRHBP antibody (AA 25-322) (ABIN6139030)

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CRHBP Antibody

Binding Specificity: AA 25-322

Sequence: YLELREAADY DPFLLFSANL KRELAGEQPY RRALRCLDML SLQGQFTFTA DRPQLHCAAF FISEPEEFIT IHYDQVSIDC QGGDFLKVFD GWILKGEKFP SSQDHPLPSA ERYIDFCESG LSRRSIRSSQ NVAMIFFRVH EPGNGFTLTI KTDPNLFPCN VISQTPNGKF TLVVPHQHRN CSFSIIYPVV IKISDLTLGH VNGLQLKKSS AGCEGIGDFV ELLGGTGLDP SKMTPLADLC YPFHGPAQMK VGCDNTVVRM VSSGKHVNRV TFEYRQLEPY ELENPNGNSI GEFCLSGL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-322 of human CRHBP (NP_001873.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRHBP

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Alternative Name: CRHBP

Background: Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.,CRHBP,CRF-BP,CRFBP,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Blood,Serum Proteins,CRHBP

Molecular Weight: 36 kDa

Gene ID: 1393

UniProt: P24387

Pathways: Negative Regulation of Hormone Secretion