CRHBP antibody (AA 70-150)
Quick Overview for CRHBP antibody (AA 70-150) (ABIN7228054)
Target
See all CRHBP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 70-150
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Purpose
- CRHBP Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of CRHBP protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human CRHBP protein at AA range: 70-150
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))
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Alternative Name
- CRHBP
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Background
- Rabbit Anti-CRHBP Polyclonal Antibody,Corticotropin-releasing hormone-binding protein, CRH-BP, Corticotropin-releasing factor-binding protein, CRF-BP, CRF-binding protein,Corticotropin-releasing hormone (CRHBP) is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.,CRHBP
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Molecular Weight
- observerd band 35kDa
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Gene ID
- 1393
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UniProt
- P24387
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Pathways
- Negative Regulation of Hormone Secretion
Target
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