CRYbB2 antibody (AA 1-205)

Catalog No. ABIN6139077

This Rabbit Polyclonal antibody specifically detects CRYbB2 in WB. It exhibits reactivity toward Human.

Quick Overview for CRYbB2 antibody (AA 1-205) (ABIN6139077)

Target: CRYbB2 (Crystallin, beta B2 (CRYbB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYbB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRYbB2 Antibody

Binding Specificity: AA 1-205

Sequence: MASDHQTQAG KPQSLNPKII IFEQENFQGH SHELNGPCPN LKETGVEKAG SVLVQAGPWV GYEQANCKGE QFVFEKGEYP RWDSWTSSRR TDSLSSLRPI KVDSQEHKII LYENPNFTGK KMEIIDDDVP SFHAHGYQEK VSSVRVQSGT WVGYQYPGYR GLQYLLEKGD YKDSSDFGAP HPQVQSVRRI RDMQWHQRGA FHPSN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human CRYBB2 (NP_000487.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRYbB2

Target: CRYbB2 (Crystallin, beta B2 (CRYbB2))

Alternative Name: CRYBB2

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts.,CRYBB2,CCA2,CRYB2,CRYB2A,CTRCT3,D22S665,CRYBB2

Molecular Weight: 23 kDa

Gene ID: 1415

UniProt: P43320