DHRS9 antibody (AA 18-319)
Quick Overview for DHRS9 antibody (AA 18-319) (ABIN6139603)
Target
See all DHRS9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 18-319
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Sequence
- RKGKLKIEDI TDKYIFITGC DSGFGNLAAR TFDKKGFHVI AACLTESGST ALKAETSERL RTVLLDVTDP ENVKRTAQWV KNQVGEKGLW GLINNAGVPG VLAPTDWLTL EDYREPIEVN LFGLISVTLN MLPLVKKAQG RVINVSSVGG RLAIVGGGYT PSKYAVEGFN DSLRRDMKAF GVHVSCIEPG LFKTNLADPV KVIEKKLAIW EQLSPDIKQQ YGEGYIEKSL DKLKGNKSYV NMDLSPVVEC MDHALTSLFP KTHYAAGKDA KIFWIPLSHM PAALQDFLLL KQKAELANPK AV
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 18-319 of human DHRS9 (NP_001135743.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:10 - 1:100
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))
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Alternative Name
- DHRS9
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Background
- This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.,DHRS9,3-alpha-HSD,3ALPHA-HSD,RDH-E2,RDH-TBE,RDH15,RDHL,RDHTBE,RETSDR8,SDR9C4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,DHRS9
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Molecular Weight
- 18 kDa/30 kDa/35 kDa/41 kDa
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Gene ID
- 10170
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UniProt
- Q9BPW9
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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