DHX30 antibody (AA 906-1155)

Catalog No. ABIN6139607

Product Details anti-DHX30 Antibody

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Binding Specificity: AA 906-1155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX30 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GWEEVLRWQD RSSRENYLEE NLLYAPSLRF IHGLIKQFSE NIYEAFLVGK PSDCTLASAQ CNEYSEEEEL VKGVLMAGLY PNLIQVRQGK VTRQGKFKPN SVTYRTKSGN ILLHKSTINR EATRLRSRWL TYFMAVKSNG SVFVRDSSQV HPLAVLLLTD GDVHIRDDGR RATISLSDSD LLRLEGDSRT VRLLKELRRA LGRMVERSLR SELAALPPSV QEEHGQLLAL LAELLRGPCG SFDVRKTADD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 906-1155 of human DHX30 (NP_055781.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DHX30

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Alternative Name: DHX30 (DHX30 Products)

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene.,DHX30,DDX30,RETCOR,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,DHX30

Molecular Weight: 129 kDa/133 kDa/136 kDa

Gene ID: 22907

UniProt: Q7L2E3

Pathways: Chromatin Binding