EBF1 antibody (C-Term)

Catalog No. ABIN6139908

The Rabbit Polyclonal anti-EBF1 antibody has been validated for WB. It is suitable to detect EBF1 in samples from Human.

Quick Overview for EBF1 antibody (C-Term) (ABIN6139908)

Target: EBF1 (Early B-Cell Factor 1 (EBF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EBF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EBF1 Antibody

Binding Specificity: C-Term

Sequence: GGSPTFLNGS AANSPYAIVP SSPTMASSTS LPSNCSSSSG IFSFSPANMV SAVKQKSAFA PVVRPQTSPP PTCTSTNGNS LQAISGMIVP PM

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human EBF1 (NP_076870.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EBF1

Target: EBF1 (Early B-Cell Factor 1 (EBF1))

Alternative Name: EBF1

Background: Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity.,EBF1,COE1,EBF,O/E-1,OLF1,Epigenetics & Nuclear Signaling,Transcription Factors,EBF1

Molecular Weight: 61 kDa/64 kDa

Gene ID: 1879

UniProt: Q9UH73