EPH Receptor B2 antibody (AA 250-540)

Catalog No. ABIN6140223

The Rabbit Polyclonal anti-EPH Receptor B2 antibody has been validated for WB. It is suitable to detect EPH Receptor B2 in samples from Human.

Quick Overview for EPH Receptor B2 antibody (AA 250-540) (ABIN6140223)

Target: EPH Receptor B2 (EPHB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor B2 Antibody

Binding Specificity: AA 250-540

Sequence: PIGRCMCKAG FEAVENGTVC RGCPSGTFKA NQGDEACTHC PINSRTTSEG ATNCVCRNGY YRADLDPLDM PCTTIPSAPQ AVISSVNETS LMLEWTPPRD SGGREDLVYN IICKSCGSGR GACTRCGDNV QYAPRQLGLT EPRIYISDLL AHTQYTFEIQ AVNGVTDQSP FSPQFASVNI TTNQAAPSAV SIMHQVSRTV DSITLSWSQP DQPNGVILDY ELQYYEKELS EYNATAIKSP TNTVTVQGLK AGAIYVFQVR ARTVAGYGRY SGKMYFQTMT EAEYQTSIQE K

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-540 of human EPHB2 (NP_059145.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPH Receptor B2

Target: EPH Receptor B2 (EPHB2)

Alternative Name: EPHB2

Background: This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.,EPHB2,CAPB,DRT,EK5,EPHT3,ERK,Hek5,PCBC,Tyro5,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,Neuron marker,Growth Cone,EPHB2

Molecular Weight: 109 kDa/110 kDa/117 kDa

Gene ID: 2048

UniProt: P29323

Pathways: RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins