EXOSC3 antibody (AA 1-275)

Catalog No. ABIN6140376

This Rabbit Polyclonal antibody specifically detects EXOSC3 in WB. It exhibits reactivity toward Human.

Quick Overview for EXOSC3 antibody (AA 1-275) (ABIN6140376)

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EXOSC3 Antibody

Binding Specificity: AA 1-275

Sequence: MAEPASVAAE SLAGSRARAA RTVLGQVVLP GEELLLPEQE DAEGPGGAVE RPLSLNARAC SRVRVVCGPG LRRCGDRLLV TKCGRLRHKE PGSGSGGGVY WVDSQQKRYV PVKGDHVIGI VTAKSGDIFK VDVGGSEPAS LSYLSFEGAT KRNRPNVQVG DLIYGQFVVA NKDMEPEMVC IDSCGRANGM GVIGQDGLLF KVTLGLIRKL LAPDCEIIQE VGKLYPLEIV FGMNGRIWVK AKTIQQTLIL ANILEACEHM TSDQRKQIFS RLAES

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human EXOSC3 (NP_057126.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXOSC3

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Alternative Name: EXOSC3

Background: This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described.,EXOSC3,CGI-102,PCH1B,RRP40,Rrp40p,bA3J10.7,hRrp-40,p10,Epigenetics & Nuclear Signaling,EXOSC3

Molecular Weight: 17 kDa/29 kDa

Gene ID: 51010

UniProt: Q9NQT5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome