FAP antibody (AA 26-280)

Catalog No. ABIN6140480

The Rabbit Polyclonal anti-FAP antibody has been validated for WB, IHC and IF. It is suitable to detect FAP in samples from Human.

Quick Overview for FAP antibody (AA 26-280) (ABIN6140480)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FAP Antibody

Binding Specificity: AA 26-280

Sequence: LRPSRVHNSE ENTMRALTLK DILNGTFSYK TFFPNWISGQ EYLHQSADNN IVLYNIETGQ SYTILSNRTM KSVNASNYGL SPDRQFVYLE SDYSKLWRYS YTATYYIYDL SNGEFVRGNE LPRPIQYLCW SPVGSKLAYV YQNNIYLKQR PGDPPFQITF NGRENKIFNG IPDWVYEEEM LATKYALWWS PNGKFLAYAE FNDTDIPVIA YSYYGDEQYP RTINIPYPKA GAKNPVVRIF IIDTTYPAYV GPQEV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-280 of human fibroblast activation protein-alpha (Fibroblast activation protein-alpha (FAP)) (NP_004451.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: FAP

Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FAP,DPPIV,FAPA,FAPalpha,SIMP,Cancer,Tumor biomarkers,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,FAP

Molecular Weight: 26 kDa/87 kDa

Gene ID: 2191

UniProt: Q12884

Pathways: Tube Formation