Fibulin 5 antibody (AA 199-448)

Catalog No. ABIN6140497

The Rabbit Polyclonal anti-Fibulin 5 antibody has been validated for WB and IF. It is suitable to detect Fibulin 5 in samples from Human.

Quick Overview for Fibulin 5 antibody (AA 199-448) (ABIN6140497)

Target: Fibulin 5 (FBLN5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Fibulin 5 Antibody

Binding Specificity: AA 199-448

Sequence: NEDGRSCQDV NECATENPCV QTCVNTYGSF ICRCDPGYEL EEDGVHCSDM DECSFSEFLC QHECVNQPGT YFCSCPPGYI LLDDNRSCQD INECEHRNHT CNLQQTCYNL QGGFKCIDPI RCEEPYLRIS DNRCMCPAEN PGCRDQPFTI LYRDMDVVSG RSVPADIFQM QATTRYPGAY YIFQIKSGNE GREFYMRQTG PISATLVMTR PIKGPREIQL DLEMITVNTV INFRGSSVIR LRIYVSQYPF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 199-448 of human FBLN5 (NP_006320.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: FBLN5

Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).,FBLN5,ADCL2,ARCL1A,ARMD3,DANCE,EVEC,FIBL-5,HNARMD,UP50,fibulin-5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Extracellular Matrix,Cardiovascular,Cardiovascular diseases,Hypertension,FBLN5

Molecular Weight: 50 kDa

Gene ID: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome