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Fibulin 5 Products

(Fibulin 5 (FBLN5))
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008].

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Featured Fibulin 5 Categories

Fibulin 5 Antibodies

High quality antibodies with extensive validation data.

Fibulin 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Fibulin 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Fibulin 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN728473
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7438958
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (2)
Cat. No. ABIN969131
Quantity 100 μL
Datasheet Datasheet

Recommended Fibulin 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955903
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966819
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966820
Quantity 96 tests
Datasheet Datasheet

Recommended Fibulin 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752787
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2721183
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404167
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Fibulin 5 products

Sun, Tomita, Salinger, Tilvawala, Li, Hakami, Liu, Tsoyi, Rosas, Reinhardt, Thompson, Ho: "PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 102, pp. 70-84, (2022) (PubMed).

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Hu, Dong, Zhao, Xu, Qin: "Fibulin-5: a novel biomarker for evaluating severity and predicting prognosis in patients with acute intracerebral haemorrhage." in: European journal of neurology, Vol. 23, Issue 7, pp. 1195-201, (2016) (PubMed).

Guo, Cheng, Chen, Xing, Xu, Feng, Qin: "Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats." in: Molecular neurobiology, (2015) (PubMed).

Sideek, Menz, Parsi, Gibson: "LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).

Albig, Neil, Schiemann: "Fibulins 3 and 5 antagonize tumor angiogenesis in vivo." in: Cancer research, Vol. 66, Issue 5, pp. 2621-9, (2006) (PubMed).

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

Synonyms and alternative names related to Fibulin 5

fibulin 5 (fbln5), fibulin 5 (FBLN5), fibulin 5 (Fbln5), A55, ADCL2, ARCL1A, ARMD3, DANCE, DKFZp469K0327, EVEC, FBLN5, FIBL-5, Fibulin-5, MGC108414, UP50, zgc:103575

Protein level used designations for Fibulin 5

  • fibulin-5
  • fibulin 5
  • fibulin-5-like
  • developmental arteries and neural crest EGF-like protein
  • urine p50 protein
  • FIBL-5
  • EVEC
  • dance
  • embryonic vascular EGF repeat-containing protein
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