FBXO31 antibody (AA 240-539)

Catalog No. ABIN6140518

The Rabbit Polyclonal anti-FBXO31 antibody is suitable to detect FBXO31 in samples from Human. It has been validated for WB.

Quick Overview for FBXO31 antibody (AA 240-539) (ABIN6140518)

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO31 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO31 Antibody

Binding Specificity: AA 240-539

Sequence: GGRQEEFRTW LREEWGRTLE DIFHEHMQEL ILMKFIYTSQ YDNCLTYRRI YLPPSRPDDL IKPGLFKGTY GSHGLEIVML SFHGRRARGT KITGDPNIPA GQQTVEIDLR HRIQLPDLEN QRNFNELSRI VLEVRERVRQ EQQEGGHEAG EGRGRQGPRE SQPSPAQPRA EAPSKGPDGT PGEDGGEPGD AVAAAEQPAQ CGQGQPFVLP VGVSSRNEDY PRTCRMCFYG TGLIAGHGFT SPERTPGVFI LFDEDRFGFV WLELKSFSLY SRVQATFRNA DAPSPQAFDE MLKNIQSLTS

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-539 of human FBXO31 (NP_079011.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXO31

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Alternative Name: FBXO31

Background: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.,FBXO31,FBX14,FBXO14,Fbx31,MRT45,pp2386,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Ubiquitin,FBXO31

Molecular Weight: 49 kDa/60 kDa

Gene ID: 79791

UniProt: Q5XUX0