FBXW5 antibody (AA 184-566)

Catalog No. ABIN6140533

The Rabbit Polyclonal anti-FBXW5 antibody is suitable to detect FBXW5 in samples from Human. It has been validated for WB.

Quick Overview for FBXW5 antibody (AA 184-566) (ABIN6140533)

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXW5 Antibody

Binding Specificity: AA 184-566

Sequence: VRNKPYDVFG CWLTETSLIS GNLHRIGDIT SCSVLWLNNA FQDVESENVN VVKRLFKIQN LNASTVRTVM VADCSRFDSP DLLLEAGDPA TSPCRIFDLG SDNEEVVAGP APAHAKEGLR HFLDRVLEGR AQPQLSERML ETKVAELLAQ GHTKPPERSA TGAKSKYLIF TTGCLTYSPH QIGIKQILPH QMTTAGPVLG EGRGSDAFFD ALDHVIDIHG HIIGMGLSPD NRYLYVNSRA WPNGAVVADP MQPPPIAEEI DLLVFDLKTM REVRRALRAH RAYTPNDECF FIFLDVSRDF VASGAEDRHG YIWDRHYNIC LARLRHEDVV NSVVFSPQEQ ELLLTASDDA TIKAWRSPRT MRVLQAPRPR PRTFFSWLAS QRR

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 184-566 of human FBXW5 (NP_061871.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXW5

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Alternative Name: FBXW5

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.,FBXW5,Fbw5,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Ubiquitin,FBXW5

Molecular Weight: 42 kDa/63 kDa

Gene ID: 54461

UniProt: Q969U6