GABBR1 antibody (AA 200-460)

Catalog No. ABIN6140882

The Rabbit Polyclonal anti-GABBR1 antibody is suitable to detect GABBR1 in samples from Human. It has been validated for WB.

Quick Overview for GABBR1 antibody (AA 200-460) (ABIN6140882)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABBR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABBR1 Antibody

Binding Specificity: AA 200-460

Sequence: EVFTSTLDDL EERVKEAGIE ITFRQSFFSD PAVPVKNLKR QDARIIVGLF YETEARKVFC EVYKERLFGK KYVWFLIGWY ADNWFKIYDP SINCTVDEMT EAVEGHITTE IVMLNPANTR SISNMTSQEF VEKLTKRLKR HPEETGGFQE APLAYDAIWA LALALNKTSG GGGRSGVRLE DFNYNNQTIT DQIYRAMNSS SFEGVSGHVV FDASGSRMAW TLIEQLQGGS YKKIGYYDST KDDLSWSKTD KWIGGSPPAD Q

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human GABBR1 (NP_068703.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Alternative Name: GABBR1

Background: This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.,GABBR1,GABABR1,GABBR1-3,GB1,GPRC3A,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GABBR1

Molecular Weight: 65 kDa/95 kDa/101 kDa/104 kDa/108 kDa

Gene ID: 2550

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process