GBA antibody (AA 40-250)

Catalog No. ABIN6140986

This anti-GBA antibody is a Rabbit Polyclonal antibody detecting GBA in WB. Suitable for Human.

Quick Overview for GBA antibody (AA 40-250) (ABIN6140986)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GBA Antibody

Binding Specificity: AA 40-250

Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA R

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.,GBA,GBA1,GCB,GLUC,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Oligodendrocyte marker,GBA

Molecular Weight: 29 kDa/50 kDa/54 kDa/57 kDa/59 kDa

Gene ID: 2629

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process