GIGYF2 antibody (AA 350-500)

Catalog No. ABIN6141083

This Rabbit Polyclonal antibody specifically detects GIGYF2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for GIGYF2 antibody (AA 350-500) (ABIN6141083)

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIGYF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GIGYF2 Antibody

Binding Specificity: AA 350-500

Sequence: VDEGEECSDS EGSHNEEAKE PDKTNKKEGE KTDRVGVASE ETPQTSSSSA RPGTPSDHQS QEASQFERKD EPKTEQTEKA EEETRMENSL PAKVPSRGDE MVADVQQPLS QIPSDTASPL LILPPPVPNP SPTLRPVETP VVGAPGMGSV S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GIGYF2

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Alternative Name: GIGYF2

Background: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.,GIGYF2,GYF2,PARK11,PERQ2,PERQ3,TNRC15,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,GIGYF2

Molecular Weight: 148 kDa/149 kDa/150 kDa/152 kDa

Gene ID: 26058

UniProt: Q6Y7W6

Pathways: Feeding Behaviour, SARS-CoV-2 Protein Interactome