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GLUL antibody (AA 1-373)

This Rabbit Polyclonal antibody specifically detects GLUL in WB, IHC and IF. It exhibits reactivity toward Human.
Catalog No. ABIN6141161

Quick Overview for GLUL antibody (AA 1-373) (ABIN6141161)

Target

See all GLUL Antibodies
GLUL (Glutamate-Ammonia Ligase (GLUL))

Reactivity

  • 51
  • 33
  • 21
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 43
  • 14
  • 1
Rabbit

Clonality

  • 42
  • 16
Polyclonal

Conjugate

  • 32
  • 7
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GLUL antibody is un-conjugated

Application

  • 44
  • 22
  • 14
  • 9
  • 8
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1-373

    Sequence

    MTTSASSHLN KGIKQVYMSL PQGEKVQAMY IWIDGTGEGL RCKTRTLDSE PKCVEELPEW NFDGSSTLQS EGSNSDMYLV PAAMFRDPFR KDPNKLVLCE VFKYNRRPAE TNLRHTCKRI MDMVSNQHPW FGMEQEYTLM GTDGHPFGWP SNGFPGPQGP YYCGVGADRA YGRDIVEAHY RACLYAGVKI AGTNAEVMPA QWEFQIGPCE GISMGDHLWV ARFILHRVCE DFGVIATFDP KPIPGNWNGA GCHTNFSTKA MREENGLKYI EEAIEKLSKR HQYHIRAYDP KGGLDNARRL TGFHETSNIN DFSAGVANRS ASIRIPRTVG QEKKGYFEDR RPSANCDPFS VTEALIRTCL LNETGDEPFQ YKN

    Cross-Reactivity

    Human, Mouse, Rat

    Characteristics

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-373 of human Glutamine Synthetase (Glutamine Synthetase (GLUL)) (NP_001028228.1).

    Isotype

    IgG
  • Application Notes

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Comment

    HIGH QUALITY

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    GLUL (Glutamate-Ammonia Ligase (GLUL))

    Alternative Name

    GLUL

    Background

    The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.,GLNS,GS,PIG43,PIG59,GLUL,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neuron marker,GLUL

    Molecular Weight

    42 kDa

    Gene ID

    2752

    UniProt

    P15104

    Pathways

    Positive Regulation of Peptide Hormone Secretion
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