GLUL antibody (AA 2-121)

Catalog No. ABIN7193662

Product Details anti-GLUL Antibody

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Binding Specificity: AA 2-121

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLUL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human GLUL (AA: 2-121) expressed in E. coli.

Clone: 2D11A2

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for GLUL

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Alternative Name: GLUL (GLUL Products)

Synonyms: GLNS antibody, GS antibody, PIG43 antibody, PIG59 antibody, Glns antibody, glns antibody, glul antibody, pig43 antibody, pig59 antibody, xgs antibody, p42 antibody, MGC64262 antibody, cb195 antibody, cb757 antibody, etID49849.2 antibody, fb39g09 antibody, fd19d09 antibody, gso1 antibody, sb:cb195 antibody, wu:fb39g09 antibody, wu:fd19d09 antibody, fb11d08 antibody, gso2 antibody, hm:zehn1949 antibody, im:7153900 antibody, wu:fb11d08 antibody, glutamate-ammonia ligase antibody, glutamate-ammonia ligase (glutamine synthetase) antibody, type I glutamate--ammonia ligase antibody, glutamate-ammonia ligase L homeolog antibody, glutamate-ammonia ligase (glutamine synthase) antibody, glutamate-ammonia ligase (glutamine synthase) a antibody, glutamate-ammonia ligase (glutamine synthase) b antibody, GLUL antibody, Glul antibody, AMF_RS09530 antibody, glul.L antibody, glul antibody, CNA04370 antibody, glula antibody, glulb antibody

Background:

Description: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Aliases: GS, GLNS, PIG43, PIG59

Molecular Weight: 42 kDa

Gene ID: 2752

Pathways: Positive Regulation of Peptide Hormone Secretion