Glutathione Reductase antibody (AA 273-522)

Catalog No. ABIN6141458

This anti-Glutathione Reductase antibody is a Rabbit Polyclonal antibody detecting Glutathione Reductase in WB. Suitable for Human.

Quick Overview for Glutathione Reductase antibody (AA 273-522) (ABIN6141458)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutathione Reductase Antibody

Binding Specificity: AA 273-522

Sequence: MISTNCTEEL ENAGVEVLKF SQVKEVKKTL SGLEVSMVTA VPGRLPVMTM IPDVDCLLWA IGRVPNTKDL SLNKLGIQTD DKGHIIVDEF QNTNVKGIYA VGDVCGKALL TPVAIAAGRK LAHRLFEYKE DSKLDYNNIP TVVFSHPPIG TVGLTEDEAI HKYGIENVKT YSTSFTPMYH AVTKRKTKCV MKMVCANKEE KVVGIHMQGL GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: GSR

Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.,GSR,HEL-75,HEL-S-122m,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,GSR

Molecular Weight: 47 kDa/50 kDa/51 kDa/53 kDa/56 kDa

Gene ID: 2936

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis